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ความคิดเห็นที่ 19 |
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The only published case involving a woman consuming ciprofloxacin who was breast feeding appeared in 1992 (14). The 4-month-old female infant was being exclusively breast-fed six times/day. The mother had taken a single nighttime dose (500 mg) of the antibacterial for 10 days prior to the collection of simultaneous samples of milk, maternal serum and infant serum, approximately 11 hours after a dose. On the day of sampling breast feeding occurred 8 hours after the mother's dose. Maternal serum, milk, and infant serum ciprofloxacin concentrations were 0.21 g/mL, 0.98 g/mL, and undetectable (<0.03 g/mL), respectively. The authors estimated the infant was consuming 0.92 mg/day (0.15 mg/kg/day) of ciprofloxacin (14). No adverse effects were observed in the infant.
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