ความคิดเห็นที่ 88
ส่วนเจ้า Imidacloprid ชื่อเรียกยากตัวนี้น่าสนใจจริงๆ ค่า LD50 สูงถึง > 5,000 mg/kg (ค่า LD50 มากๆยิ่งดี แสดงว่าความเป็นพิษน้อยลง เพราะต้องใช้สารถึง 5000 mg ถึงจะทำให้หนูทดลองตายได้ 50% ของประชากรที่ทดสอบ) เดี๋ยวต้องไปหาข้อมูลเพิ่มว่า ราคาเท่าไร กับผลงานกำจัดปลวกเป็นอย่างไร
Imidacloprid is rated as "moderately toxic" acutely by the World Health Organization and the United States Environmental Protection Agency‎ (class II or III, requiring a "Warning" or "Caution" label), and a "potential" ground water contaminant. It is rated as an "unlikely" carcinogen by the EPA (group E), and is not listed for endocrine, reproductive, or developmental toxicity, or as a chemical of special concern by any agencies. It is not banned, restricted, canceled, or illegal to import in any country. Tolerances for Imidacloprid residue in food range from 0.02 mg/kg in eggs to 3.0 mg/kg in hops.
Animal toxicity is similar to that of the parent compound, nicotine; fatigue, twitching, cramps, and weakness leading to asphyxia. The oral LD50 of imidacloprid is 450 mg/kg body weight in rats and 131 mg/kg in mice; the 24-hour dermal LD50 in rats is greater than >5000 mg/kg. It is not irritating to eyes or skin in rabbits and guinea pigs (although some commercial preparations contain clay as an inert ingredient, which may be an irritant). The acute inhalation LD50 in rats was not reached at the greatest attainable concentrations, 69 milligrams per cubic meter of air as an aerosol, and 5,323 mg/m³ of air as a dust. In rats subjected to a two year feeding study, no observable effect was seen at 100 parts per million (ppm). At 300 ppm females showed decreased body weight gain and males showed increased thyroid lesions, while females showed increased thyroid lesions at 900 ppm. In :-) year feeding study in dogs, no observable effect was seen at 1,250 ppm, while levels up to 2,500 ppm led to hypercholesterolemia and elevated liver cytochrome p-450 measurements. Reproductive studies in rats resulted in no observable effect at 100 ppm and decreased pup weight at 250 ppm; developmental toxicity studies in rats showed no observable effect at 30 (mg/kg)/day and skeletal anomalies at 100 (mg/kg)/day, while in rabbits no observable effect was detected at 24 (mg/kg)/day and skeletal abnormalities at 72 (mg/kg)/day. Imidacloprid was negative for mutagenicity in 21 out of 23 different laboratory tests, but was positive for chromosomal changes in human lymphocytes and for genotoxicity in CHO cells. No carcinogenicity was seen in rats fed up to 1,800 mg/kg of imidacloprid for two years.[6]
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คนปากช่อง (super yellow bird)
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26 พ.ค. 52 07:48:39
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